Long-term Preservation of Renin-secreting Ability by Human Adult Juxtaglomerular Tumor Cells in Explant Culture

propagation of human germ stem cells in long-term culture

background: spermatogonial stem cells (sscs), a subset of undifferentiated type a spermatogonia, are the foundation of complex process of spermatogenesis and could be propagated in vitro culture conditions for long time for germ cell transplantation and fertility preservation. objective: the aim of this study was in vitro propagation of human spermatogonial stem cells (sscs) and improvement of ...

Renin‑secreting juxtaglomerular cell tumor of the kidney causing severe hypertension and polyuria.

Renin biosynthesis by human tumoral juxtaglomerular cells. Evidences for a renin precursor.

Renin biosynthesis was studied in a juxtaglomerular cell tumor. The tumoral tissue had a high renin content (180 Goldblatt Units/g of tissue), was heavily stained by immunofluorescence using human renin antiserum, and exhibited numerous characteristic secretory granules by electron microscopy. In one series of experiments, renin biosynthesis was studied in tissue slices, by following the incorp...

Renin-secreting tumor. Case report.

Renin-secreting tumor, though rare, should be considered in assessing severe hyperreninemic, hypertensive patients. We studied an 18-year-old girl with hypokalemic hyperreninemic hyperaldosteronism. No angiographic lesion could be detected. The plasma renin activity (PRA) of the right/left renal vein was 7.3. With a presumptive diagnosis of renin-secreting tumor (RST), the patient was operated ...

Electrophysiology of the renin-producing juxtaglomerular cells.

Renin is an aspartyl-proteinase hormone that is produced, stored and released by juxtaglomerular (JG) granular cells in the distal part of the renal afferent arterioles. The rate of secretion of renin from JG cells is one of the main determinants of the overall activity of the renin-angiotensin system, and is the most well regulated parameter of all constituents of that system. At least three c...